Adjuvant questions.

Adjuvant ipilimumab in stage III melanoma: New landscape, new questions.

The recently reported significant prolongation of overall survival with ipilimumab as adjuvant in high-risk stage III melanoma patients represents an important event in the adjuvant treatment landscape. The European Organisation for Research and Treatment of Cancer 18071 trial demonstrated a 28% reduction in risk of death in patients treated with ipilimumab at 10 mg/kg (hazard ratio for death, ...

E-Learning: some unanswered questions

Asthma: Achievements and Questions in Front

       Asthma, which is mainly distinguished by airway inflammation and bronchial hyper responsiveness, is known as one of the most common chronic diseases worldwide. It also is the most frequent chronic respiratory disorder amongst all age groups. On one side of the asthma story, there are massive investment of time, effort and money, a large number of pharmaceutical and academic research stud...

Answering Questions about Questions: A Persuasion Knowledge Perspective for Understanding the Effects of Rhetorical Questions

Past research is not clear on the process by which rhetorical questions influence persuasion (i.e., increased focus on message arguments vs. on the persuasion agent). Based on recent theories of persuasion knowledge and rhetorical figures in advertising, our model delineates conditions under which rhetoricals are likely to enhance argument elaboration (low salience of the rhetorical) and those ...

Questions Pool

1. In class we defined the statistical (also known as variational) distance between two distributions A and B taking values in U to be |A− B| = maxT⊆U |Pr[A ∈ T ]− Pr[B ∈ T ]|. A× B denotes the distribution on (a, b) obtained by independently picking a according to A and b according to B. (A,B) denotes some random variable on U × U with marginal distributions A and B. For f : U → U ′ and A that...